Recent Publications | Center for Cerebellar Network Structure/Function in Health and Disease

Center for Cerebellar Structure and Function

Recent Cerebellum and Related Publications from Center Members:

Adanyeguh, I. M., Joers, J. M., Deelchand, D. K., Hutter, D. H., Eberly, L. E., Guo, B., Iltis, I., Bushara, K. O., Henry, P. G., & Lenglet, C. (2023). Brain MRI detects early-stage alterations and disease progression in Friedreich ataxia. Brain communications, https://doi.org/10.1093/braincomms/fcad196

Hengel, H., Martus, P., Faber, J., Giunit, P., Garcia-Moreno, H., Solanky, N., Klockgether, T., Reetz, K., van de Warrenburg, B. P., Santana, M. M., Silva, P., Cunha, I., de Almeida, L. P., Timmann, D., Infante, J., de Vries, J., Lima, M., Pires, P., Bushara, K., Jacobi, H., … Schöls, L. (2023). The frequency of non-motor symptoms in SCA3 and their association with disease severity and lifestyle factors. Journal of neurology, https://doi.org/10.1007/s00415-022-11441-z

Nanclares, C., Noriega-Prieto, J. A., Labrada-Moncada, F. E., Cvetanovic, M., Araque, A., & Kofuji, P. (2023). Altered calcium signaling in Bergmann glia contributes to spinocerebellar ataxia type-1 in a mouse model of SCA1. Neurobiology of disease, https://doi.org/10.1016/j.nbd.2023.106318

Soles, A., Selimovic, A., Sbrocco, K., Ghannoum, F., Hamel, K., Moncada, E. L., Gilliat, S., & Cvetanovic, M. (2023). Extracellular Matrix Regulation in Physiology and in Brain Disease. International journal of molecular sciences, https://doi.org/10.3390/ijms24087049

Mathews, P. J., Paradis, A. L., Cvetanovic, M., Carlson, E. S., & Parker, K. L. (2023). Editorial: Unraveling the complex and multifaceted role of the cerebellum in health and disease. Frontiers in systems neuroscience, https://doi.org/10.3389/fnsys.2023.1155939

Cvetanovic, M., & Gray, M. (2023). Contribution of Glial Cells to Polyglutamine Diseases: Observations from Patients and Mouse Models. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, https://doi.org/10.1007/s13311-023-01357-5

Duvick, L., Southern, W. M., Benzow, K., Burch, Z. N., Handler, H. P., Mitchell, J. S., Kuivinen, H., Gadiparthi, U. K., Yang, P., Soles, A., Scheeler, C., Rainwater, O., Serres, S., Lind, E., Nichols-Meade, T., O'Callaghan, B., Zoghbi, H. Y., Cvetanovic, M., Wheeler, V. C., Ervasti, J. M., … Orr, H. T. (2023). Delineating regional vulnerability in the neurodegenerative disease SCA1 using a conditional mutant ATXN1 mouse. bioRxiv : the preprint server for biology, https://doi.org/10.1101/2023.02.08.527710

Rosa, J. G., Hamel, K., Soles, A., Sheeler, C., Borgenheimer, E., Gilliat, S., Sbrocco, K., Ghanoum, F., Handler, H. P., Forster, C., Rainwater, O., & Cvetanovic, M. (2023). BDNF is altered in a brain-region specific manner and rescues deficits in Spinocerebellar Ataxia Type 1. Neurobiology of disease, https://doi.org/10.1016/j.nbd.2023.106023

Handler, H. P., Duvick, L., Mitchell, J. S., Cvetanovic, M., Reighard, M., Soles, A., Mather, K. B., Rainwater, O., Serres, S., Nichols-Meade, T., Coffin, S. L., You, Y., Ruis, B. L., O'Callaghan, B., Henzler, C., Zoghbi, H. Y., & Orr, H. T. (2023). Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles. Neuron, https://doi.org/10.1016/j.neuron.2022.11.017

McLoughlin, H. S., Gundry, K., Rainwater, O., Schuster, K. H., Wellik, I. G., Zalon, A. J., Benneyworth, M. A., Eberly, L. E., & Öz, G. (2023). Antisense Oligonucleotide Silencing Reverses Abnormal Neurochemistry in Spinocerebellar Ataxia 3 Mice. Annals of neurology, 94(4), 658–671. https://doi.org/10.1002/ana.26713

Deelchand, D. K., Eberly, L. E., McCarten, J. R., Hemmy, L. S., Auerbach, E. J., & Marjańska, M. (2023). Scyllo-inositol: Transverse relaxation time constant at 3 T and concentration changes associated with aging and alcohol use. NMR in biomedicine, https://doi.org/10.1002/nbm.4929

Pisharady, P. K., Eberly, L. E., Adanyeguh, I. M., Manousakis, G., Guliani, G., Walk, D., & Lenglet, C. (2023). Multimodal MRI improves diagnostic accuracy and sensitivity to longitudinal change in amyotrophic lateral sclerosis. Communications medicine, https://doi.org/10.1038/s43856-023-00318-5

Guo, B., Eberly, L. E., Henry, P. G., Lenglet, C., & Lock, E. F. (2023). Multiway sparse distance weighted discrimination. Journal of computational and graphical statistics, https://doi.org/10.1080/10618600.2022.2099404

Zarate, N., Gundry, K., Yu, D., Casby, J., Eberly, L. E., Öz, G., & Gomez-Pastor, R. (2023). Neurochemical correlates of synapse density in a Huntington's disease mouse model. Journal of neurochemistry, https://doi.org/10.1111/jnc.15714

Hope, J., Beckerle, T., Cheng, P. H., Viavattine, Z., Feldkamp, M., Fausner, S., Saxena, K., Ko, E., Hryb, I., Carter, R., Ebner, T., & Kodandaramaiah, S. (2023). Brain-wide neural recordings in mice navigating physical spaces enabled by a cranial exoskeleton. bioRxiv : the preprint server for biology, https://doi.org/10.1101/2023.06.04.543578

Nietz, A. K., Streng, M. L., Popa, L. S., Carter, R. E., Flaherty, E. B., Aronson, J. D., & Ebner, T. J. (2023). To be and not to be: wide-field Ca2+ imaging reveals neocortical functional segmentation combines stability and flexibility. Cerebral cortex, https://doi.org/10.1093/cercor/bhac523

West, S. L., Gerhart, M. L., & Ebner, T. J. (2023). Wide-field calcium imaging of cortical activation and functional connectivity in externally- and internally-driven locomotion. Research square, https://doi.org/10.21203/rs.3.rs-2776902/v1

Gray, M. M., Naik, A., Ebner, T. J., & Carter, R. E. (2023). Altered brain state during episodic dystonia in tottering mice decouples primary motor cortex from limb kinematics. Dystonia, https://doi.org/10.3389/dyst.2023.10974

Cramer, S. W., Haley, S. P., Popa, L. S., Carter, R. E., Scott, E., Flaherty, E. B., Dominguez, J., Aronson, J. D., Sabal, L., Surinach, D., Chen, C. C., Kodandaramaiah, S. B., & Ebner, T. J. (2023). Wide-field calcium imaging reveals widespread changes in cortical functional connectivity following mild traumatic brain injury in the mouse. Neurobiology of disease, https://doi.org/10.1016/j.nbd.2022.105943

Brændholt, M., Kluger, D. S., Varga, S., Heck, D. H., Gross, J., & Allen, M. G. (2023). Breathing in waves: Understanding respiratory-brain coupling as a gradient of predictive oscillations. Neuroscience and biobehavioral reviews, https://doi.org/10.1016/j.neubiorev.2023.105262

Beckinghausen, J., Ortiz-Guzman, J., Lin, T., Bachman, B., Salazar Leon, L. E., Liu, Y., Heck, D. H., Arenkiel, B. R., & Sillitoe, R. V. (2023). The cerebellum contributes to generalized seizures by altering activity in the ventral posteromedial nucleus. Communications biology, https://doi.org/10.1038/s42003-023-05100-w

Allen, M., Varga, S., & Heck, D. H. (2023). Respiratory rhythms of the predictive mind. Psychological review, https://doi.org/10.1037/rev0000391

Heck, D. H., Fox, M. B., Correia Chapman, B., McAfee, S. S., & Liu, Y. (2023). Cerebellar control of thalamocortical circuits for cognitive function: A review of pathways and a proposed mechanism. Frontiers in systems neuroscience, https://doi.org/10.3389/fnsys.2023.1126508

Heck, D. H., & Varga, S. (2023). "The great mixing machine": multisensory integration and brain-breath coupling in the cerebral cortex. Pflugers Archiv : European journal of physiology, https://doi.org/10.1007/s00424-022-02738-z

Adanyeguh, I. M., Henry, P. G., & Deelchand, D. K. (2023). Prospective motion correction for cervical spinal cord MRS. Magnetic resonance in medicine, https://doi.org/10.1002/mrm.29836

Öz, G., Cocozza, S., Henry, P. G., Lenglet, C., Deistung, A., Faber, J., Schwarz, A. J., Timmann, D., Van Dijk, K. R. A., Harding, I. H., & AGI Working Group on MRI Biomarkers (2023). Correction to: MR Imaging in Ataxias: Consensus Recommendations by the Ataxia Global Initiative Working Group on MRI Biomarkers. Cerebellum (London, England), https://doi.org/10.1007/s12311-023-01589-3

Rezende, T. J. R., Adanyeguh, I. M., Arrigoni, F., Bender, B., Cendes, F., Corben, L. A., Deistung, A., Delatycki, M., Dogan, I., Egan, G. F., Göricke, S. L., Georgiou-Karistianis, N., Henry, P. G., Hutter, D., Jahanshad, N., Joers, J. M., Lenglet, C., Lindig, T., Martinez, A. R. M., Martinuzzi, A., … França, M. C., Jr (2023). Progressive Spinal Cord Degeneration in Friedreich's Ataxia: Results from ENIGMA-Ataxia. Movement disorders : official journal of the Movement Disorder Society, https://doi.org/10.1002/mds.29261

Kauppinen, R. A., Thothard, J., Leskinen, H. P. P., Pisharady, P. K., Manninen, E., Kettunen, M., Lenglet, C., Gröhn, O. H. J., Garwood, M., & Nissi, M. J. (2023). Axon fiber orientation as the source of T1 relaxation anisotropy in white matter: A study on corpus callosum in vivo and ex vivo. Magnetic resonance in medicine, https://doi.org/10.1002/mrm.29667

Kauppinen, R. A., Thotland, J., Pisharady, P. K., Lenglet, C., & Garwood, M. (2023). White matter microstructure and longitudinal relaxation time anisotropy in human brain at 3 and 7 T. NMR in biomedicine, https://doi.org/10.1002/nbm.4815

Wei, C., Benzow, K., Koob, M. D., Gomez, C. M., & Du, X. (2023). The Transcription Factor, α1ACT, Acts Through a MicroRNA Network to Regulate Neurogenesis and Cell Death During Neonatal Cerebellar Development. Cerebellum (London, England), https://doi.org/10.1007/s12311-022-01431-2

Streng, M. L., Froula, J. M., & Krook-Magnuson, E. (2023). The cerebellum's understated role and influences in the epilepsies. Neurobiology of disease, https://doi.org/10.1016/j.nbd.2023.106160

Liu, M., Liu, H., Feng, F., Krook-Magnuson, E., & Dudley, S. C. (2023). TRPM7 kinase mediates hypomagnesemia-induced seizure-related death. Scientific reports, https://doi.org/10.1038/s41598-023-34789-2

Stieve, B. J., Smith, M. M., & Krook-Magnuson, E. (2023). LINCs Are Vulnerable to Epileptic Insult and Fail to Provide Seizure Control via On-Demand Activation. eNeuro, https://doi.org/10.1523/ENEURO.0195-22.2022

Thompson, L. M., & Orr, H. T. (2023). HD and SCA1: Tales from two 30-year journeys since gene discovery. Neuron, https://doi.org/10.1016/j.neuron.2023.09.036

Orr H. T. (2023). Cholecystokinin Activation of Cholecystokinin 1 Receptors: a Purkinje Cell Neuroprotective Pathway. Cerebellum (London, England), https://doi.org/10.1007/s12311-022-01428-x

Bartelt, L. C., Switonski, P. M., Adamek, G., Carvalho, J., Duvick, L. A., Jarrah, S. I., McLoughlin, H. S., Scoles, D. R., Pulst, S. M., Orr, H. T., Hull, C., Lowe, C. B., & La Spada, A. R. (2023). Purkinje-Enriched snRNA-seq in SCA7 Cerebellum Reveals Zebrin Identity Loss as a Central Feature of Polyglutamine Ataxias. bioRxiv : the preprint server for biology, https://doi.org/10.1101/2023.03.19.533345

Coffin, S. L., Durham, M. A., Nitschke, L., Xhako, E., Brown, A. M., Revelli, J. P., Villavicencio Gonzalez, E., Lin, T., Handler, H. P., Dai, Y., Trostle, A. J., Wan, Y. W., Liu, Z., Sillitoe, R. V., Orr, H. T., & Zoghbi, H. Y. (2023). Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron, https://doi.org/10.1016/j.neuron.2023.02.030

Buchholz, M., Weber, N., Rädke, A., Faber, J., Schmitz-Hübsch, T., Jacobi, H., Xie, F., Klockgether, T., Michalowsky, B., EUROSCA study group, & ESMI study group (2023). Health-Related Quality of Life in Patients with Spinocerebellar Ataxia: a Validation Study of the EQ-5D-3L. Cerebellum (London, England), https://doi.org/10.1007/s12311-023-01597-3

Mengel, D., Wellik, I. G., Schuster, K. H., Jarrah, S. I., Wacker, M., Ashraf, N. S., Öz, G., Synofzik, M., Costa, M. D. C., & McLoughlin, H. S. (2023). Blood levels of neurofilament light are associated with disease progression in a mouse model of spinocerebellar ataxia type 3. Disease models & mechanisms, https://doi.org/10.1242/dmm.050144

Peek, A. L., Rebbeck, T. J., Leaver, A. M., Foster, S. L., Refshauge, K. M., Puts, N. A., Oeltzschner, G., & MRS Expert Panel (2023). A comprehensive guide to MEGA-PRESS for GABA measurement. Analytical biochemistry, https://doi.org/10.1016/j.ab.2023.115113

Faber, J., Berger, M., Carlo, W., Hübener-Schmid, J., Schaprian, T., Santana, M. M., Grobe-Einsler, M., Onder, D., Koyak, B., Giunti, P., Garcia-Moreno, H., Gonzalez-Robles, C., Lima, M., Raposo, M., Melo, A. R. V., de Almeida, L. P., Silva, P., Pinto, M. M., van de Warrenburg, B. P., van Gaalen, J., … Klockgether, T. (2023). Stage-dependent biomarker changes in spinocerebellar ataxia type 3. medRxiv : the preprint server for health sciences, https://doi.org/10.1101/2023.04.21.23287817

Chao, O. Y., Pathak, S. S., Zhang, H., Augustine, G. J., Christie, J. M., Kikuchi, C., Taniguchi, H., & Yang, Y. M. (2023). Social memory deficit caused by dysregulation of the cerebellar vermis. Nature communications, https://doi.org/10.1038/s41467-023-41744-2

Levings, D. C., Pathak, S. S., Yang, Y. M., & Slattery, M. (2023). Limited Expression of Nrf2 in Neurons Across the Central Nervous System. bioRxiv : the preprint server for biology, https://doi.org/10.1101/2023.05.09.540014

Wang, S. Y., Yao, X., Yang, Y. M., Chen, D., Wang, R. W., & Xie, F. J. (2023). Super-rational aspiration promotes cooperation in the asymmetric game with peer exit punishment and reward. Heliyon, https://doi.org/10.1016/j.heliyon.2023.e16729

Chao, O. Y., Nikolaus, S., Yang, Y. M., & Huston, J. P. (2022). Neuronal circuitry for recognition memory of object and place in rodent models. Neuroscience and biobehavioral reviews, https://doi.org/10.1016/j.neubiorev.2022.104855

Abdelfattah AS, Ahuja S, Akkin T, et al. (2022) Neurophotonic tools for microscopic measurements and manipulation: status report. Neurophotonics. doi:10.1117/1.NPh.9.S1.013001

Joers, J. M., Adanyeguh, I. M., Deelchand, D. K., Hutter, D. H., Eberly, L. E., Iltis, I., Bushara, K. O., Lenglet, C., & Henry, P. G. (2022). Spinal cord magnetic resonance imaging and spectroscopy detect early-stage alterations and disease progression in Friedreich ataxia. Brain communications, https://doi.org/10.1093/braincomms/fcac246

Park, Y. W., Joers, J. M., Guo, B., Hutter, D., Bushara, K., Adanyeguh, I. M., Eberly, L. E., Öz, G., & Lenglet, C. (2022). Corrigendum: Assessment of cerebral and cerebellar white matter microstructure in spinocerebellar ataxias 1, 2, 3, and 6 using diffusion MRI. Frontiers in neurology, https://doi.org/10.3389/fneur.2022.1038298

Rodden, L. N., Rummey, C., Dong, Y. N., Lagedrost, S., Regner, S., Brocht, A., Bushara, K., Delatycki, M. B., Gomez, C. M., Mathews, K., Murray, S., Perlman, S., Ravina, B., Subramony, S. H., Wilmot, G., Zesiewicz, T., Bolotta, A., Domissy, A., Jespersen, C., Ji, B., … Lynch, D. R. (2022). A non-synonymous single nucleotide polymorphism in SIRT6 predicts neurological severity in Friedreich ataxia. Frontiers in molecular biosciences, https://doi.org/10.3389/fmolb.2022.933788

Rummey C, Corben LA, Delatycki M, Wilmot G, Subramony SH, Corti M, Bushara K, Duquette A, Gomez C, Hoyle JC, Roxburgh R, Seeberger L, Yoon G, Mathews K, Zesiewicz T, Perlman S, Lynch DR (2022). Natural History of Friedreich's Ataxia: Heterogeneity of Neurological Progression and Consequences for Clinical Trial Design. Neurology. doi: 10.1212/WNL.0000000000200913.

Maas RPPWM, Teerenstra S, Lima M, Pires P, Pereira de Almeida L, van Gaalen J, Timmann D, Infante J, Onyike C, Bushara K, Jacobi H, Reetz K, Santana MM, Afonso Ribeiro J, Hübener-Schmid J, de Vries JJ, Synofzik M, Schöls L, Garcia-Moreno H, Giunti P, Faber J, Klockgether T, van de Warrenburg BPC.(2022) Differential Temporal Dynamics of Axial and Appendicular Ataxia in SCA3. Movement disorders : official journal of the Movement Disorder Society, doi: 10.1002/mds.29135.

Hengel H, Martus P, Faber J, Garcia-Moreno H, Solanky N, Giunti P, Klockgether T, Reetz K, van de Warrenburg BP, Pereira de Almeida L, Santana MM, Januário C, Silva P, Thieme A, Infante J, de Vries J, Lima M, Ferreira AF, Bushara K, Jacobi H, Onyike C, Schmahmann JD, Hübener-Schmid J, Synofzik M, Schöls L.(2022) Characterization of Lifestyle in Spinocerebellar Ataxia Type 3 and Association with Disease Severity. Mov Disord. doi: 10.1002/mds.28844.

Nietz, A. K., Popa, L. S., Streng, M. L., Carter, R. E., Kodandaramaiah, S. B., & Ebner, T. J. (2022). Wide-Field Calcium Imaging of Neuronal Network Dynamics In Vivo. Biology, https://doi.org/10.3390/biology11111601

Donaldson, P. D., Navabi, Z. S., Carter, R. E., Fausner, S. M. L., Ghanbari, L., Ebner, T. J., Swisher, S. L., & Kodandaramaiah, S. B. (2022). Polymer Skulls With Integrated Transparent Electrode Arrays for Cortex-Wide Opto-Electrophysiological Recordings. Advanced healthcare materials, https://doi.org/10.1002/adhm.202200626

Liu, Y., McAfee, S. S., Van Der Heijden, M. E., Dhamala, M., Sillitoe, R. V., & Heck, D. H. (2022). Causal Evidence for a Role of Cerebellar Lobulus Simplex in Prefrontal-Hippocampal Interaction in Spatial Working Memory Decision-Making. Cerebellum (London, England), https://doi.org/10.1007/s12311-022-01383-7

Heck, D. H., Correia, B. L., Fox, M. B., Liu, Y., Allen, M., & Varga, S. (2022). Recent insights into respiratory modulation of brain activity offer new perspectives on cognition and emotion. Biological psychology, https://doi.org/10.1016/j.biopsycho.2022.108316

Taylor, A. P., Lee, A. S., Goedecke, P. J., Tolley, E. A., Joyner, A. L., & Heck, D. H. (2022). Conditional loss of Engrailed1/2 in Atoh1-derived excitatory cerebellar nuclear neurons impairs eupneic respiration in mice. Genes, brain, and behavior, https://doi.org/10.1111/gbb.12788

McAfee, S. S., Liu, Y., Sillitoe, R. V., & Heck, D. H. (2022). Cerebellar Coordination of Neuronal Communication in Cerebral Cortex. Frontiers in systems neuroscience, https://doi.org/10.3389/fnsys.2021.781527

Pandolfo, M., Reetz, K., Darling, A., Rodriguez de Rivera, F. J., Henry, P. G., Joers, J., Lenglet, C., Adanyeguh, I., Deelchand, D., Mochel, F., Pousset, F., Pascual, S., Van den Eede, D., Martin-Ugarte, I., Vilà-Brau, A., Mantilla, A., Pascual, M., Martinell, M., Meya, U., & Durr, A. (2022). Efficacy and Safety of Leriglitazone in Patients With Friedreich Ataxia: A Phase 2 Double-Blind, Randomized Controlled Trial (FRAMES). Neurology. Genetics, https://doi.org/10.1212/NXG.0000000000200034

Georgiou-Karistianis, N., Corben, L. A., Reetz, K., Adanyeguh, I. M., Corti, M., Deelchand, D. K., Delatycki, M. B., Dogan, I., Evans, R., Farmer, J., França, M. C., Gaetz, W., Harding, I. H., Harris, K. S., Hersch, S., Joules, R., Joers, J. J., Krishnan, M. L., Lax, M., Lock, E. F., … Henry, P. G. (2022). A natural history study to track brain and spinal cord changes in individuals with Friedreich's ataxia: TRACK-FA study protocol. PloS one, https://doi.org/10.1371/journal.pone.0269649

Fang, K., Liu, D., Pathak, S. S., Yang, B., Li, J., Karthikeyan, R., Chao, O. Y., Yang, Y. M., Jin, V. X., & Cao, R. (2021). Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice. Cells, https://doi.org/10.3390/cells10123314

Deng, Y. H., Yang, Y. M., Ruan, J., Mu, L., & Wang, S. Q. (2021). Effects of nursing care in fast-track surgery on postoperative pain, psychological state, and patient satisfaction with nursing for glioma. World journal of clinical cases, https://doi.org/10.12998/wjcc.v9.i20.5435

Rummey C, Flynn JM, Corben LA, Delatycki MB, Wilmot G, Subramony SH, Bushara K, Duquette A, Gomez CM, Hoyle JC, Roxburgh R, Seeberger L, Yoon G, Mathews KD, Zesiewicz T, Perlman S, Lynch DR. (2021) Scoliosis in Friedreich's ataxia: longitudinal characterization in a large heterogeneous cohort. Ann Clin Transl Neurol. doi: 10.1002/acn3.51352.

Wang Y, Gao Z, Han Z, Liu Y, Yang H, Akkin T, Hogan CJ, Bischof JC. (2021) Aggregation affects optical properties and photothermal heating of gold nanospheres. Sci Rep. doi: 10.1038/s41598-020-79393-w.

Harding, I. H., Chopra, S., Arrigoni, F., Boesch, S., Brunetti, A., Cocozza, S., Corben, L. A., Deistung, A., Delatycki, M., Diciotti, S., Dogan, I., Evangelisti, S., França, M. C., Jr, Göricke, S. L., Georgiou-Karistianis, N., Gramegna, L. L., Henry, P. G., Hernandez-Castillo, C. R., Hutter, D., Jahanshad, N., … Thompson, P. M. (2021). Brain Structure and Degeneration Staging in Friedreich Ataxia: Magnetic Resonance Imaging Volumetrics from the ENIGMA-Ataxia Working Group. Annals of neurology, https://doi.org/10.1002/ana.26200

Perissinotti, P. P., Martínez-Hernández, E., He, Y., Koob, M. D., & Piedras-Rentería, E. S. (2021). Genetic Deletion of KLHL1 Leads to Hyperexcitability in Hypothalamic POMC Neurons and Lack of Electrical Responses to Leptin. Frontiers in neuroscience, https://doi.org/10.3389/fnins.2021.718464

Yang, Y. M., Arsenault, J., Bah, A., Krzeminski, M., Fekete, A., Chao, O. Y., Pacey, L. K., Wang, A., Forman-Kay, J., Hampson, D. R., & Wang, L. Y. (2020). Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain. Molecular psychiatry, https://doi.org/10.1038/s41380-018-0240-0

Chao, O. Y., de Souza Silva, M. A., Yang, Y. M., & Huston, J. P. (2020). The medial prefrontal cortex - hippocampus circuit that integrates information of object, place and time to construct episodic memory in rodents: Behavioral, anatomical and neurochemical properties. Neuroscience and biobehavioral reviews, https://doi.org/10.1016/j.neubiorev.2020.04.007

Chao, O. Y., Marron Fernandez de Velasco, E., Pathak, S. S., Maitra, S., Zhang, H., Duvick, L., Wickman, K., Orr, H. T., Hirai, H., & Yang, Y. M. (2020). Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, https://doi.org/10.1038/s41386-020-0656-5

Hashem V, Tiwari A, Bewick B, Teive HAG, Moscovich M, Schüle B, Bushara K, Bower M, Rasmussen A, Tsai YC, Clark T, McFarland K, Ashizawa T. (2020) Correction: Pulse-Field capillary electrophoresis of repeat-primed PCR amplicons for analysis of large repeats in Spinocerebellar Ataxia Type 10. PLoS One. doi: 10.1371/journal.pone.0231746.

Gan SR, Figueroa KP, Xu HL, Perlman S, Wilmot G, Gomez CM, Schmahmann J, Paulson H, Shakkottai VG, Ying SH, Zesiewicz T, Bushara K, Geschwind MD, Xia G, Subramony SH, Rosenthal L, Ashizawa T, Pulst SM, Wang N, Kuo SH. (2020) The impact of ethnicity on the clinical presentations of spinocerebellar ataxia type 3. Parkinsonism Relat Disord. doi: 10.1016/j.parkreldis.2020.02.004.

Yang CY, Lai RY, Amokrane N, Lin CY, Figueroa KP, Pulst SM, Perlman S, Wilmot G, Gomez CM, Schmahmann JD, Paulson H, Shakkottai VG, Rosenthal LS, Ying SH, Zesiewicz T, Bushara K, Geschwind M, Xia G, Subramony SH, Ashizawa T, Troche MS, Kuo SH. (2020) Dysphagia in spinocerebellar ataxias type 1, 2, 3 and 6. J Neurol Sci. doi: 10.1016/j.jns.2020.116878.

Liu, Y., Qi, S., Thomas, F., Correia, B. L., Taylor, A. P., Sillitoe, R. V., & Heck, D. H. (2020). Loss of cerebellar function selectively affects intrinsic rhythmicity of eupneic breathing. Biology open, https://doi.org/10.1242/bio.048785

Castro, M., Venkateswaran, N., Peters, S. T., Deyle, D. R., Bower, M., Koob, M. D., Boeve, B. F., & Vossel, K. (2020). Case Report: Early-Onset Behavioral Variant Frontotemporal Dementia in Patient With Retrotransposed Full-Length Transcript of Matrin-3 Variant 5. Frontiers in neurology, https://doi.org/10.3389/fneur.2020.600468

Martínez-Hernández, E., Zeglin, A., Almazan, E., Perissinotti, P., He, Y., Koob, M., Martin, J. L., & Piedras-Rentería, E. S. (2020). KLHL1 Controls CaV3.2 Expression in DRG Neurons and Mechanical Sensitivity to Pain. Frontiers in molecular neuroscience, https://doi.org/10.3389/fnmol.2019.00315

Gamache, J. E., Kemper, L., Steuer, E., Leinonen-Wright, K., Choquette, J. M., Hlynialuk, C., Benzow, K., Vossel, K. A., Xia, W., Koob, M. D., & Ashe, K. H. (2020). Developmental Pathogenicity of 4-Repeat Human Tau Is Lost with the P301L Mutation in Genetically Matched Tau-Transgenic Mice. The Journal of neuroscience : the official journal of the Society for Neuroscience, https://doi.org/10.1523/JNEUROSCI.1256-19.2019

Liu CJ, Shamsan GA, Akkin T, Odde DJ. (2019) Glioma Cell Migration Dynamics in Brain Tissue Assessed by Multimodal Optical Imaging. Biophys J. doi:10.1016/j.bpj.2019.08.010

u Montcel ST, Petit E, Olubajo T, Faber J, Lallemant-Dudek P, Bushara K, Perlman S, Subramony S, Morgan D, Jackman B, Paulson H, Öz G, Klockgether T, Durr A, Ashizawa T, on behalf of READISCA Consortium Collaborators (2023) Baseline clinical and blood biomarker in patients with preataxic and early-stage disease spinocerebellar ataxia 1 and 3. Neurology, DOI: 10.1212/WNL.0000000000207088.

Froula J, Hastings S, Krook-Magnuson E (2023) The little brain and the seahorse: cerebellar-hippocampal interactions. Frontiers in Systems Neuroscience doi: 10.3389/fnsys.2023.1158492

Jayashree Chandrasekaran, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M Joers, Dinesh K Deelchand, Michal Považan, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Pierrick Coupé, Chiadi U Onyike, Peter B Barker, Jeremy D Schmahmann, Eva-Maria Ratai, S H Subramony, Thomas H Mareci, Khalaf O Bushara, Henry Paulson, Alexandra Durr, Thomas Klockgether, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz; READISCA Consortium (2022) Clinically Meaningful Magnetic Resonance Endpoints Sensitive to Preataxic Spinocerebellar Ataxia Types 1 and 3. Ann Neurol. doi: 10.1002/ana.26573

Jennifer Faber, David Kügler, Emad Bahrami, Lea-Sophie Heinz, Dagmar Timmann, Thomas M Ernst, Katerina Deike-Hofmann, Thomas Klockgether, Bart van de Warrenburg, Judith van Gaalen, Kathrin Reetz, Sandro Romanzetti, Gulin Oz, James M Joers, Jorn Diedrichsen; ESMI MRI Study Group; Martin Reuter (2022) CerebNet: A fast and reliable deep-learning pipeline for detailed cerebellum sub-segmentation. Neuroimage. doi: 10.1016/j.neuroimage.2022.119703

Selvadurai LP, Perlman SL, Wilmot GR, Subramony SH, Gomez CM, Ashizawa T, Paulson HL, Onyike CU, Rosenthal LS, Sair HI, Kuo SH, Ratai EM, Zesiewicz TA, Bushara KO, Öz G, Dietiker C, Geschwind MD, Nelson AB, Opal P, Yacoubian TA, Nopoulos PC, Shakkottai VG, Figueroa KP, Pulst SM, Morrison PE, Schmahmann JD (2022) The S-Factor, a New Measure of Disease Severity in Spinocerebellar Ataxia: Findings and Implications. Cerebellum. doi: 10.1007/s12311-022-01424-1.

Stieve B, Richner T, Krook-Magnuson C, Netoff T, Krook-Magnuson E (2022) Optimization of closed-loop electrical stimulation enables robust cerebellar-directed seizure control. Brain. doi.org/10.1093/brain/awac051

Streng M, Tetzlaff M, Krook-Magnuson E (2021) Distinct fastigial output channels and their impact on temporal lobe seizures. Journal of Neuroscience. doi: 10.1523/JNEUROSCI.0683-21.2021

West SL, Aronson JD, Popa LS, Carter RE, Shekhar A, Feller KD, Ghanbari L, Kodandaramaiah SB, Ebner TJ (2021) Wide-field calcium imaging of dynamic cortical networks during locomotion. Cerebral Cortex. doi: 10.1093/cercor/bhab373

Chao OY, Zhang H, Pathak SS, Huston JP, Yang YM (2021) Functional Convergence of Motor and Social Processes in Lobule IV/V of the Mouse Cerebellum. Cerebellum. doi: 10.1007/s12311-021-01246-7.

Harding et al (2021) Brain Structure and Degeneration Staging in Friedreich Ataxia: Magnetic Resonance Imaging Volumetrics from the ENIGMA-Ataxia Working Group. Annals of Neurology doi: 10.1002/ana.26200

Asher M, Rosa JG, Cvetanovic M. (2021) Mood alterations in mouse models of Spinocerebellar Ataxia type 1, Sci Rep. Jan 12;11(1):713. doi: 10.1038/s41598-020-80664-9

Faber J, Schaprian T, Koyak B, Reetz K, França Jr MC, Rezende TJR, Hong J, Liao W, van de Warrenburg B, van Gaalen, J, Durr A, Mochel F, Giunti P, Garcia-Moreno H, Schoels L, Hengel H, Synofzik M, Bender B, Öz G, Joers J, de Vries JJ, Kang J, Timmann-Braun D, Jacobi H, Infante J, Joules R, Romanzetti S, Diedrichsen J, Schmid M, Wolz R, Klockgether T (2021) Regional brain and spinal cord volume loss in spinocerebellar ataxia type 3, Mov Disord. doi: 10.1002/mds.28610.

Cramer SW, Carter RE, Aronson JD, Kodandaramaiah SB, Ebner TJ, Chen CC (2021) Through the looking glass: A review of cranial window technology for optical access to the brain. J Neurosci Methods. doi.org/10.1016/j.jneumeth.2021.109100

Koscik TR, Sloat L, van der Plas E, Joers JM, Deelchand DK, Lenglet C, Öz G, Nopoulos PC (2020) Brainstem and striatal volume changes are detectable in under one year and predict motor decline in SCA1, Brain Commun. https://doi.org/10.1093/braincomms/fcaa184.

Asher M, Rosa JG, Rainwater O, Duvick L, Bennyworth M, Lai RY, CRC-SCA, Kuo SH, Cvetanovic M (2020) Cerebellar contribution to the cognitive alterations in SCA1: evidence from mouse models, Hum Mol Genet, vol. 29, no. 1, pp. 117-131. https://doi.org/10.1093/hmg/ddz265

Zeidler Z, Hoffmann K, Krook-Magnuson E (2020) HippoBellum: acute cerebellar modulation alters hippocampal dynamics and function, Journal of Neuroscience. 40 (36): 6910-6926. https://doi.org/10.1523/JNEUROSCI.0763-20.2020

Chao OY, Marron Fernandez de Velasco E, Pathak SS, Maitra S, Zhang H, Duvick L, Wickman K, Orr HT, Hirai H, Yang YM (2020) Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism. Neuropsychopharmacology. doi: 10.1038/s41386-020-0656-5.

Hamel KA, Cvetanovic M. (2020) Cerebellar Regional Dissection for Molecular Analysis, J Vis Exp. Dec 5;(166):10.3791/61922. doi: 10.3791/61922

Nietz A, Krook-Magnuson C, Gutierrez H, Klein J, Sauve C, Hoff I, Christenson Wick Z, Krook-Magnuson E (2020) Selective loss of the GABA_Aα1 subunit from Purkinje cells is sufficient to induce a tremor phenotype, Journal of Neurophysiology, Published on-line Sept 9, 2020. https://doi.org/10.1152/jn.00100.2020

Carmo Costa M, Radzwion M, McLoughlin HS, Ashraf NS, Fischer S, Shakkottai VG, Maciel P, Paulson HL, Öz G (2020) In vivo molecular signatures of cerebellar pathology in spinocerebellar ataxia type 3, Mov Disord, 35(10):1774-1786. doi: 10.1002/mds.28140

Streng ML, Krook-Magnuson E (2020) The cerebellum and epilepsy, Epilepsy & Behavior; https://doi.org/10.1016/j.yebeh.2020.106909

Öz G, Harding IH, Krahe J, Reetz K (2020) MR Imaging and Spectroscopy in Degenerative Ataxias: Towards Multi-modal, Multi-site, Multi-stage Monitoring of Neurodegeneration, Curr Opin Neurol, 33(4):451-461.

Streng ML, Krook-Magnuson E (2020) Excitation, but not inhibition of the fastigial nucleus provides powerful control over temporal lobe seizures, J Physiol 598(1): 171-187.

Park YW, Joers JM, Guo B, Hutter D, Bushara K, Adanyeguh IM, Eberly LE, Öz G, Lenglet C (2020) Assessment of Cerebral and Cerebellar White Matter Microstructure in Spinocerebellar Ataxias 1, 2, 3 and 6 using diffusion MRI, Front Neurol - Applied Neuroimaging, 11:411.

Yang YM, Arsenault J, Bah A, Krzeminski M, Fekete A, Chao OY, Pacey LK, Wang A, Forman-Kay J, Hampson DR, Wang LY (2020) Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain. Mol Psychiatry. doi: 10.1038/s41380-018-0240-0.

Ghanbari L, Carter RE, Rynes ML, Dominguez J, Chen G, Naik A, Hu J, Sagar MAK, Haltom L, Mossazghi N, Gray MM, West SL, Eliceiri KW, Ebner TJ, Kodandaramaiah SB (2019) Cortex-wide neural interfacing via transparent polymer skulls. Nat Commun. doi: 10.1038/s41467-019-09488-0

Deelchand DK, Joers JM, Ravishankar A, Lyu T, Emir UE, Hutter D, Gomez CM, Bushara KO, Lenglet C, Eberly LE, Öz G (2019) Sensitivity of MRI volumetry and MRS to progression of spinocerebellar ataxia type 1, Mov Disord Clin Pract, 6(7):549-558.

Li T, Liu CJ, Akkin T (2019) Contrast-enhanced serial optical coherence scanner with deep learning network reveals vasculature and white matter organization of mouse brain, Neurophotonics, 6(3): 035004.

Popa LS, Ebner TJ (2019) Cerebellum, Predictions and Errors. Front Cell Neurosci. doi: 10.3389/fncel.2018.00524. eCollection 2018.

Popa LS, Streng ML, Ebner TJ (2019) Purkinje Cell Representations of Behavior: Diary of a Busy Neuron. Neuroscientist. Jun;25(3):241-257. doi: 10.1177/1073858418785628. Epub 2018 Jul 9